Tales of Monkey Island Episode 101 Launch of the Screaming

While explosively stripping the evil pirate LeChuck of his
demonic mojo, Guybrush Threepwood inadvertently infects the
entire Caribbean with the arch-fiend's expelled voodoo, which
threatens to transform buccaneers into unruly pirate monsters.
Pursued by a notorious cut-throat Pirate Hunter and a creepy
French Physician who believes that Guybrush's eerily-infected
hand holds the secret of eternal life, Threepwood sails the seven
seas in search of La Esponja Grande, a legendary sea sponge with
unparalleled voodoo exfoliating abilities. But little does
Guybrush know, his quest is part of a larger, more sinister plot,
and good and evil are not always as they seem?

Who can Guybrush trust? Where can he turn? Everything you think
you know will be challenged as Tales of Monkey Island builds to
its unexpected finale!